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Sam is the name of various characters on Casualty. Sam could refer to:
- Sam Nicholls, a registrar and later paramedic who worked in the ED from 2011 to 2013 and with the ambulance service from 2017.
- Sam Bateman, the son of Tess Bateman and a recurring guest character from 2004-2015.
- Sam Colloby, the Project 2000 nurse who worked in the ED from 1996 to 1999.
- Sam Strachan, the ex-lover of Connie Beauchamp and the father of Grace, and Medical Director in 2017.