"Episode One" is the 1049th episode of Casualty and the premiere of the 32nd series. It was preceded by "One" and followed by "Episode Two". The episode was directed by Steve Brett and written by Dana Fainaru. This episode is the first of two episodes partially taking place in France. This episode features the final appearance of Grace Beauchamp, portrayed by Emily Carey, after almost three years as a recurring guest character on the show.
Both episode one and two of the series were filmed in Wales, not on-location in France.
During production, this episode's title was "Dr Dylan". However, when the decision was made not to have episode titles for the series, this name was scrapped.